I'm based in New York City, and I've been working remotely for a company based in San Francisco for two and a half years now.

Personally, I find it's been overall a net benefit to my career, though that's not to say remote work is for everyone, or that every company is structured to provide career opportunities for people who work remotely.

I actually wrote in more detail about my experience and the things I've learned in the process which have helped make remote working work well for me. https://adityamukerjee.net/2017/10/03/remote-work-2-years-in...