My rule: If you do what your body was made to do, and you do it in balance you'll feel better and be more healthy. It's a bitter pill to swallow for our generation, but our bodies weren't meant to sit looking at a screen 12 hours a day.
Currently trying that myself, it's actually quite pleasant so far. I just put my desk up on cinder blocks to raise it to elbow level. If I like it I'll find a less ghetto solution.