Are there really that many popular extensions not available on Firefox? I may be just one anecdote, but I think I'm pretty typical, and I've found the transition to Firefox to be quite pleasant, and uneventful.
Popular - no. Essential - yes. Case in point - my bank (top 5 in my country) which uses Chrome plugin for security purposes, you need it to create digital signature. So once a year I HAVE to install Chrome (key expires every year) and then delete it. I've also found at least one payment processor not working in Firefox, my city portal for public transport and several small sites. The worrying thing is the trend - with Firefox share dropping below 10% recently it will be abandoned more and more.
My issue is with certain sites that typically either uses non standard Javascript apis that only work in blink or relies on non standard behavior of standard components (numeric form inputs was mentioned here yesterday).