Malaria prophylaxis is pretty rough in and of itself, and it's not really recommended unless you're going to be in high-risk areas (source, tried to get it myself when going into Mozambique from South Africa, was told there that unless I was planning to stay "in the bush" for a few weeks, it was a bad idea)

South African here. Fact is most of our country is malaria free, the cities etc especially so. It’s only in the hottest, most humid part of the Bush that you will get the mosquitos, and then generally in summer.

When I travelled to Kenya last year my wife and I took malaria medication, we would do the same if going to a malaria area in SA in summer.

Yeah, we were not worried in SA. We were in Nelspruit, going to Maputo, and asked for it there, and that was the response we got.