CSS was designed for running on different UAs and there is special mechanism built in it. If you take a look into source of that demo page, you will see:
You should not assume that all browsers support same set of features. And needless to say, that Sciter is not a universal browser. And so is Cobalt in that respect - it is a browser for particular site / application.
Yes, a return to the dark days of UAs having their own proprietary extensions / prefixes to do the same thing. Why bother when there's an actual industry standard?
> You should not assume that all browsers support same set of features.
You can certainly target only user agents which support CSS Flexbox. I would even say it's the advisable default unless you have some very special needs.
That's a critical distinction when you want to run the same codebase as you have on the web.