I think Datomic is potentially disruptive and represents some great thinking on the part of an individual. Whether it will be disruptive will hinge on how well that thinking has subsumed the years of industry experience and practicalities, not to forget the conservative approach to data. I'd be interested to see how it pans out.

I think if will also be imortend what other databases come out of this. There is space for other prioritys in terms of CAP in a world were perseption and process are seperated. Or just other implmentations of the same ideas, opensource maybe.

If you want to be conservative about your data, it looks like Datomic is an excellent choice. It preserves the entire history of your data instead of allowing it to be modified in place.

Conservative generally means using tried and tested technologies that has run stably for years on thousands of servers and where every corner case is well documented and well understood. Not using some new largely untested technology that sounds awesome on paper, but has yet to truly prove itself in the real world.

Disclaimer: I'm a huge fan of clojure and Hickey and I think Datomic sounds amazing. I'm currently looking for an excuse to play with Datomic and learn more about it, so don't take what I said as any indication that I'm somehow against Datomic.