(Kidding, its a nice analogy but I think its also good to do some research on the tools you might need first or you might waste a lot of time. I once wasted a month of development time because I picked the wrong toolbox for the job).
its a new account. today there was a discussion about django, and i like django. surely i'll discuss other things on other days. why do you care anyway?
The "tool" analogy breaks down somewhat in that what we're really talking about are building standards and frameworks. If you build your home as an insulated concrete form to European green standards, you can't simply start building the rest as a stick and plaster home if you find that your needs change or your understanding of ICF wasn't complete. If you did you would end up with a mishmashed hodgepodge that ends up being the worst of both.
2. Pick the tools you like. Get a good hammer, saw, adjustable square.
3. Leave Home Depot and go get good with them.
4. If something breaks or doesn't perform a task you need, go back to Home Depot to supplement your toolbox.