You will notice the difference if you ever want to move your music to a better format in the future (due to transcoding losses). With FLAC you would not have this problem.
This is true, I do eventually want to move it to opus if they ever resolve the random seek issues with the codec since it gets better compression ratios and more importantly is open.
But I also figure my 60gb of mp3s would be at least 400gb or more as flac, though given how cheap storage space is that may not be an issue. I guess I should start trying to collect flac music after all!