What he/she really means is that it's not profitable. Wet leases are used to fill in gaps for airlines, you don't build an entire airline out of wet leases. If you did you're not doing much other than being a middle man doing bookings for other airlines, and you probably won't be able to compete on price.
Major commercial air travel is a commodity business. Where opportunity lies is perhaps in offering air travel solutions that bypass the hassle of airports. Shuttles between SF, LA or Houston and Dallas for example. These are heavily trafficked routes with mostly business travelers who would love to avoid long security lines and drive right up to a plane at a small airport.
