I have an interesting anecdote related to ketosis: I was in nutritional ketosis for three months to test its effects on my body. My ketones were consistent with being in the ketotic state, but my LDL-P and triglycerides skyrocketed with no meaningful improvement in HDL. It's debatable whether this is "bad" for you without inflammation (atherosclerosis relies on both), but I certainly wasn't comfortable with the elevated levels and went out of ketosis.
Saturated fat sensitivity seems to have been my issue (VERY difficult to be on that diet without high levels of saturated fat) and I'm now on a low-carb monounsaturated fat diet that has dramatically improved my blood lipids.
So, for me at least, I would have to disagree with "the rest is just calories" statement. I think too many people are trying to simplify nutrition with a single book, diet, or pill, when in reality, it's a complex system that might very well be impossible to predict.
Saturated fat sensitivity seems to have been my issue (VERY difficult to be on that diet without high levels of saturated fat) and I'm now on a low-carb monounsaturated fat diet that has dramatically improved my blood lipids.
So, for me at least, I would have to disagree with "the rest is just calories" statement. I think too many people are trying to simplify nutrition with a single book, diet, or pill, when in reality, it's a complex system that might very well be impossible to predict.