If there are specific keys for the macros, I'd agree. Otherwise you'll never even more modifier combos, like the Poker 2 macros...

Can you give an example? Are macro keys used for doing several keystrokes with one key?

Some razer keyboards and corsair keyboards have them. You program them using the software to whatever keystrokes you want. When pressed they do them. For example, I have one set to do $. Another to ctrl,alt,del.